Experimental and clinical background

Validation in experimental studies

In vitro and in vivo experimental studies have shown a pathophysiological role of ApoJ-Glyc in ischemic disease.

Link to publication

01

Early decrease in ApoJ-Glyc circulating levels upon ischemia induction

02

Intracellular accumulation of ApoJ-Glyc upon ischemia induction

03

Progressive decrease of ApoJ-Glyc release with ischemia

Our studies have demonstrated for the first time the association between decreased ApoJ-Glyc levels and ischemia induced changes in cardiac cells

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